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Compounded Semaglutide + B12 vial on a mirror disc, studio render
Compounded Semaglutide + B12 vial, illustration: Solution

RxWeight loss · 503A

Semaglutide + B12

Compounded semaglutide with vitamin B12, prepared as a ready solution.

Strength & form
$722 mg · 2 mL · Solution
Consult first
Compounded Semaglutide + B12 vial on a mirror disc, studio render
Protocol
Semaglutide + B12
Care path
Weight loss
Strength
2 mg · 2 mL
Source
503A
Dispensing
Rx only

Before you consult

Start from
your numbers.

Your physician looks at BMI alongside your history, conditions and current medicines. Set yours.

Nothing you enter leaves this page. Not a diagnosis.

Instrument · BMI

Body mass index

The process · Semaglutide + B12

Your first
90 days.

From consult to refill: what happens, in order, and who decides. Timing depends on your physician and your protocol.

Physician’s decision

Step 01 of 07: Consult · async $39 · sync $49

Consult a physician

Start with an async consult ($39): a physician reviews your intake and history, no appointment needed.

State rules decide what can be prescribed where you live.Which consult?

Step 02 of 07: Decision · your physician

Physician review

Your physician reviews your history and decides whether Semaglutide + B12 is right for you. Prescription items ship only after a physician approves them.

Your physician may ask for a live visit or labs before prescribing.

Step 03 of 07: Pharmacy · 503A

Compounded for you

A state-licensed 503A compounding pharmacy prepares Semaglutide + B12 for you, under your physician’s prescription. Compounded medications are made for an individual patient and are not FDA-approved drug products.

Step 04 of 07: Shipping · to your door

Shipped to your door

Once your physician approves it, your order ships to your door. Storage and handling instructions come with your prescription.

Step 05 of 07: First dose · solution

Ready to measure

It arrives as a ready solution in a sealed multi-dose vial: nothing to reconstitute.

Syringes and swabs are on the store as a $20 starter kit.Starter kit ↗

Step 06 of 07: Check-in · physician’s decision

Adjusted by your physician

Your physician sets the starting dose and changes it as you go. Any change to your dose is your physician’s decision.

Never change a dose without talking to your physician.

Step 07 of 07: Refill · Patient Support

Your next vial

How long a vial lasts depends on the dose and schedule your physician sets.

  1. 01 Consult
  2. 02 Review
  3. 03 Pharmacy
  4. 04 Shipping
  5. 05 First dose
  6. 06 Check-ins
  7. 07 Refills

01Overview

A compounded formulation that combines semaglutide with vitamin B12 in one solution, prepared by a state-licensed 503A compounding pharmacy.

Your physician decides whether this formulation is right for you and sets the dose.

Dispensed as
Compounded Semaglutide + B12
Strengths
2 mg · 2 mL (solution)
4 mg · 2 mL (solution)
10 mg · 2 mL (solution)
Route
Subcutaneous injection
Sourcing
Prepared by a state-licensed 503A compounding pharmacy
Access
Prescription only, after a physician consult

02Structure

Fig. 04 · SemaglutideC₁₈₇H₂₉₁N₄₅O₅₉

3D model

HAibEGTFTSDVSSYLEGQAAKEFIAWLVRGRG

K20 — γGlu–2×OEG–C18 diacid

31 amino acids: the sequence of GLP-1 (7–37) with two substitutions, Aib at position 2 and arginine at position 28 (Ala8 and Lys34 in GLP-1 numbering). Lysine 20 carries a C18 fatty diacid through a γGlu–2×OEG linker. The solution also contains vitamin B12, a separate small molecule that is not part of the peptide shown.

Ref. PubChem CID 56843331 · RCSB PDB-101 · 3D fold drawn schematically

03How it’s taken

Subcutaneous injection. Your physician sets the dose and the schedule, and explains how to prepare and give each dose. Never change a dose without talking to your physician.

It comes as a ready solution in a multi-dose vial: no reconstitution needed. Syringes and swabs are on the store as a $20 starter kit ↗.

Storage and handling instructions come with your prescription.

04How you get it

  1. Select your state. State rules decide what can be prescribed where you live.
  2. Consult a physician. Start with an async consult ($39) or a live consult ($49).
  3. Physician review. Your physician decides whether Semaglutide + B12 is right for you and writes the prescription.
  4. Shipped to your door. Once approved, your order ships. Patient Support is at +1 (888) 471-9962.

05Sourcing

503A

A state-licensed 503A compounding pharmacy prepares the medication for you, under your physician’s prescription. Compounded medications are made for an individual patient and are not FDA-approved drug products.

06Questions

Do I need a prescription for Semaglutide + B12?

Yes. Semaglutide + B12 is prescription-only. Start with an async consult ($39) or a live consult ($49). A licensed physician reviews your history and decides whether it is right for you.

Which strengths are available?

On our store: 2 mg · 2 mL solution, $72; 4 mg · 2 mL solution, $96; 10 mg · 2 mL solution, $144. Your physician decides which strength and schedule fit your protocol.

How does it arrive?

As a ready solution in a sealed multi-dose vial, so there is nothing to reconstitute. Your prescription explains how to measure each dose.

Who makes it?

A state-licensed 503A compounding pharmacy prepares the medication for you, under your physician’s prescription. Compounded medications are made for an individual patient and are not FDA-approved drug products.

How long does a vial last?

It depends on the dose and schedule your physician sets. Patient Support can help at +1 (888) 471-9962.

07Safety

Important safety information

Compounded semaglutide is not FDA-approved and is not the same as any FDA-approved semaglutide product. The FDA has not reviewed it for safety, effectiveness or quality.

FDA-approved semaglutide carries a boxed warning about thyroid C-cell tumors. It is not used by anyone with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or with a serious allergy to it.

Other serious risks include pancreatitis, gallbladder problems, low blood sugar (especially with insulin or a sulfonylurea), kidney problems from dehydration, serious allergic reactions, worsening diabetic eye disease, and changes in mood or thoughts. Tell your physician before any surgery or sedation.

The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain. Not for use during pregnancy. Call your physician right away about severe stomach pain, a lump or swelling in your neck, or trouble swallowing or breathing.

Compounded medications are prepared by state-licensed pharmacies for individual patients. They are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness or quality. This page is general information and does not replace a consultation with a licensed physician, who decides whether a treatment is appropriate for you.